HIV Positive Model
 
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About ISENTRESS HD
HIV Positive Model
 
ISENTRESS HD may help lower viral load.

In the 48-week ONCEMRK clinical study Research that studies whether a treatment is safe and effective for people to use. X of adults who were new to HIV-1 treatment, the percentage of patients reaching an undetectable viral load was:

89% of patients taking ISENTRESS HD + Truvada vs 88% of patients taking ISENTRESS + Truvada.

ISENTRESS HD may not have these effects in all patients.

How ISENTRESS HD was studied:

The ONCEMRK trial compared the safety and efficacy of ISENTRESS HD versus ISENTRESS over 48 weeks in adults who were new to HIV-1 treatment.

531 adults took ISENTRESS HD + Truvada (another HIV-1 medicine)

266 adults took ISENTRESS + Truvada

Patients were assigned by chance to take one of two treatment regimens, and neither the patients nor the doctors taking part in the study knew which regimen they were taking.

ISENTRESS HD has a low rate of side effects.

The most common side effects When a medicine has a different effect on you than it was meant to have. Side effects can be unpleasant. They can make it hard for you to do your daily activities.X of ISENTRESS HD include trouble sleeping, headache, dizziness, nausea, and tiredness. These are not all of the possible side effects of ISENTRESS HD.

Some side effects can be serious.

ISENTRESS and ISENTRESS HD can cause serious side effects including:

Severe skin reactions and allergic reactions

If you develop a rash, call your doctor right away. Stop using ISENTRESS HD and call your doctor or get medical help right away if you develop a rash with:

Fever

Generally ill feeling

Extreme tiredness

Muscle or joint aches

Blisters or sores in mouth

Blisters or peeling of the skin

Redness or swelling of the eyes

Swelling of the mouth, lips, or face

Problems breathing

 

As some of these reactions can be severe and may be life-threatening.

Liver problems

Call your doctor right away if you have any of the following signs or symptoms:

Yellowing of your skin or the whites of your eyes

Dark or tea-colored urine

Pale colored stools (bowel movements)

Nausea or vomiting

Loss of appetite

Pain, aching, or tenderness on the right side of your stomach area

Changes in your immune system

Tell your doctor right away if you start having:

New symptoms after starting your HIV-1 medicine

 
REMEMBER!

Tell your healthcare team about any side effects you may be experiencing. They may be able to help.

REMEMBER! Tell your healthcare team about any side effects you may be experiencing. They may be able to help.
 
 
ISENTRESS HD can be used with a wide range of non-HIV medicines.

Some medicines interact with ISENTRESS HD. Tell your doctor if you take: antacids containing aluminum, magnesium, or calcium; rifampin; tipranavir/ritonavir; etravirine; or other drugs such as carbamazepine, phenobarbital, and phenytoin. It is not recommended to take these medicines with ISENTRESS HD. Your doctor will tell you if it’s safe to take ISENTRESS HD with other medicines.

Do not start any new medicines while you are taking ISENTRESS HD without first talking with your doctor.

Tell your doctor about all medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements.

Keep a list of your medicines to show your doctor and pharmacist.

 

 
 

WHAT IS ISENTRESS OR ISENTRESS HD

WHAT IS ISENTRESS

OR ISENTRESS HD

ISENTRESS is a prescription HIV medicine used with other antiretroviral medicines to treat human immunodeficiency virus-1 (HIV-1) infection in adults, and in children weighing at least 4.4 pounds (2 kg). ISENTRESS HD is a prescription HIV medicine used with other antiretroviral medicines to treat HIV-1 infection in adults, and in children weighing at least 88 pounds (40 kg). HIV is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

ISENTRESS should not be used in children weighing less than 4.4 pounds (2 kg).

 
 
 

IMPORTANT

SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION

Some people who take ISENTRESS or ISENTRESS HD develop severe skin reactions and allergic reactions that can be serious, and may be life-threatening or lead to death. If you develop a rash, call your doctor right away. If you develop a rash with any of the following symptoms, stop using ISENTRESS or ISENTRESS HD and call your doctor or get medical help right away: fever; generally ill feeling; extreme tiredness; muscle or joint aches; blisters or sores in mouth; blisters or peeling of skin; redness or swelling of the eyes; swelling of the mouth, lips, or face; problems breathing.

Sometimes allergic reactions can affect body organs, such as your liver. Call your doctor right away if you have any of the following signs or symptoms of liver problems: yellowing of your skin or whites of your eyes; dark or tea-colored urine; pale-colored stools (bowel movements); nausea or vomiting; loss of appetite; pain, aching, or tenderness on the right side of your stomach area.

Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV-1 medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Tell your doctor right away if you start having new symptoms after starting your HIV-1 medicine.

People taking ISENTRESS or ISENTRESS HD may still develop infections or other conditions associated with HIV-1 infections.

The most common side effects of ISENTRESS or ISENTRESS HD include: trouble sleeping, headache, dizziness, nausea, and tiredness. Less common side effects include: depression, hepatitis, genital herpes, herpes zoster including shingles, kidney failure, kidney stones, indigestion or stomach area pain, vomiting, suicidal thoughts and actions, and weakness.

Tell your doctor before you take ISENTRESS or ISENTRESS HD if you have a history of a muscle disorder called rhabdomyolysis or myopathy or increased levels of creatine kinase in your blood.

Tell your doctor right away if you get unexplained muscle pain, tenderness, or weakness while taking ISENTRESS or ISENTRESS HD. These may be signs of a rare serious muscle problem that can lead to kidney problems.

These are not all the possible side effects of ISENTRESS or ISENTRESS HD. For more information, ask your doctor or pharmacist. Tell your doctor if you have any side effect that bothers you or that does not go away.

Tell your doctor about all your medical conditions, including if you have any allergies, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. ISENTRESS and ISENTRESS HD are not recommended for use during pregnancy. Do not breastfeed if you take ISENTRESS or ISENTRESS HD. Women with HIV should not breastfeed because their babies could be infected with HIV through their breast milk.

Tell your doctor about all the medicines you take, including, prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines interact with ISENTRESS or ISENTRESS HD. Do not start taking a new medicine without telling your doctor. Your doctor can tell you if it is safe to take ISENTRESS or ISENTRESS HD with those other medicines.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call FDA at 1-800-FDA-1088.

Please read the accompanying Patient Information and Instructions for Use for ISENTRESS and ISENTRESS HD and discuss them with your doctor. The physician Prescribing Information also is available.

Having trouble paying for your Merck medicine? Merck may be able to help. www.merckhelps.com

Brands mentioned are the trademarks of their respective owners.


 

WHAT IS ISENTRESS
OR ISENTRESS HD 

ISENTRESS is a prescription HIV medicine used with other antiretroviral medicines to treat human

ISENTRESS is a prescription HIV medicine used with other antiretroviral medicines to treat human immunodeficiency virus-1 (HIV-1) infection in adults, and in children weighing at least 4.4 pounds (2 kg). ISENTRESS HD is a prescription HIV

ISENTRESS is a prescription HIV medicine used with other antiretroviral medicines to treat human immunodeficiency virus-1 (HIV-1) infection in adults, and in children weighing at least 4.4 pounds (2 kg). ISENTRESS HD is a prescription HIV medicine used with other antiretroviral medicines to treat HIV-1 infection in adults, and in children weighing at least 88 pounds (40 kg). HIV is the virus that causes AIDS (Acquired Immune Deficiency Syndrome).

ISENTRESS should not be used in children weighing less than 4.4 pounds (2 kg).

 
 

IMPORTANT

 

SAFETY INFORMATION

IMPORTANT SAFETY INFORMATION  

Some people who take ISENTRESS or ISENTRESS HD develop severe skin reactions and allergic reactions that can be serious, and may be life-threatening or

Some people who take ISENTRESS or ISENTRESS HD develop severe skin reactions and allergic reactions that can be serious, and may be life-threatening or lead to death. If you develop a rash, call your doctor right away. If you develop a rash with any of the following symptoms, stop using ISENTRESS or ISENTRESS HD and call your doctor or get medical

Some people who take ISENTRESS or ISENTRESS HD develop severe skin reactions and allergic reactions that can be serious, and may be life-threatening or lead to death. If you develop a rash, call your doctor right away. If you develop a rash with any of the following symptoms, stop using ISENTRESS or ISENTRESS HD and call your doctor or get medical help right away: fever; generally ill feeling; extreme tiredness; muscle or joint aches; blisters or sores in mouth; blisters or peeling of skin; redness or swelling of the eyes; swelling of the mouth, lips, or face; problems breathing.

Sometimes allergic reactions can affect body organs, such as your liver. Call your doctor right away if you have any of the following signs or symptoms of liver problems: yellowing of your skin or whites of your eyes; dark or tea-colored urine; pale-colored stools (bowel movements); nausea or vomiting; loss of appetite; pain, aching, or tenderness on the right side of your stomach area.

Changes in your immune system (Immune Reconstitution Syndrome) can happen when you start taking HIV-1 medicines. Your immune system may get stronger and begin to fight infections that have been hidden in your body for a long time. Tell your doctor right away if you start having new symptoms after starting your HIV-1 medicine.

People taking ISENTRESS or ISENTRESS HD may still develop infections or other conditions associated with HIV-1 infections.

The most common side effects of ISENTRESS or ISENTRESS HD include: trouble sleeping, headache, dizziness, nausea, and tiredness. Less common side effects include: depression, hepatitis, genital herpes, herpes zoster including shingles, kidney failure, kidney stones, indigestion or stomach area pain, vomiting, suicidal thoughts and actions, and weakness.

Tell your doctor before you take ISENTRESS or ISENTRESS HD if you have a history of a muscle disorder called rhabdomyolysis or myopathy or increased levels of creatine kinase in your blood.

Tell your doctor right away if you get unexplained muscle pain, tenderness, or weakness while taking ISENTRESS or ISENTRESS HD. These may be signs of a rare serious muscle problem that can lead to kidney problems.

These are not all the possible side effects of ISENTRESS or ISENTRESS HD. For more information, ask your doctor or pharmacist. Tell your doctor if you have any side effect that bothers you or that does not go away.

Tell your doctor about all your medical conditions, including if you have any allergies, are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed. ISENTRESS and ISENTRESS HD are not recommended for use during pregnancy. Do not breastfeed if you take ISENTRESS or ISENTRESS HD. Women with HIV should not breastfeed because their babies could be infected with HIV through their breast milk.

Tell your doctor about all the medicines you take, including, prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines interact with ISENTRESS or ISENTRESS HD. Do not start taking a new medicine without telling your doctor. Your doctor can tell you if it is safe to take ISENTRESS or ISENTRESS HD with those other medicines.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call FDA at 1-800-FDA-1088.

Please read the accompanying Patient Information and Instructions for Use for ISENTRESS and ISENTRESS HD and discuss them with your doctor. The physician Prescribing Information also is available.

Having trouble paying for your Merck medicine? Merck may be able to help. www.merckhelps.com

Brands mentioned are the trademarks of their respective owners.


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